The most commonly advertised contraindication is a personal or family history of medullary thyroid carcinoma (MTC) or multiple endocrine neoplasia syndrome type 2
In general, a high-calorie, high-fat diet characterized by high intakes of sugar, refined carbohydrates, saturated fat, cholesterol, and trans fats has been linked to an increased risk of gallstones and their complications (Compagnucci 2016
NaBPC157 In addition to a decrease of the otherwise raised blood pressure values, NaBPC157 also caused a marked attenuation or even abolition of the lesions and disturbances normally appearing in the various organs which were (after three weeks of an increased salt diet in the controls): very severe hyaline degeneration with prominent parenhymaous hemorrhages, degeneration of the arterial walls, vacuolisation of the cells in the heart, severe congestion (specifically medullar) in the adrenals, severe congestion, parenhymatous hemorrhage with hematuria in kidney and hemosiderosis and erythrocytophagia in the spleen
The regulatory landscape continues to evolve
Not sure if it is because of the Kirkman product or because the first bottle of 3% compound cream got rid of the top layer of pigmentation which would be easier to remove