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Immunohistochemical staining and western blot analysis revealed that SNL increased the activation of microglia and astrocytes in the dentate gyrus of the hippocampus, along with elevated expression of pro-inflammatory cytokines such as TNF-, IL-1 and IL-6, which were significantly reversed by exendin-4 treatment [68]

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This could be possible when SeNP-MT could stabilize the aquaporin or downregulate the ROS induced breakdown of membrane proteins those collectively improved the root hydraulic conductivity

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