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The propensity scores were modeled using a machine learning method called eXtreme Gradient Boosting (XGBoost), which uses a decision tree ensemble approach to optimize the balance of baseline covariates utilized for matching
Tirzepatide (LY3298176) in Participants With Type 2 Diabetes Not Controlled With Diet and Exercise Alone (SURPASS) studies have shown that tirzepatide reduced HbA1c and fasting glucose levels more than the titrated insulin degludec, insulin glargine or 1 mg once a week semaglutide independently of the baseline levels of HbA1c
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