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Reduced Formation of 1-Methylnicotinamide Researchers use reduced 1-methylnicotinamide as a pharmacodynamic marker that NNMT activity has been inhibited

Phase 4: AOD 9604 cycle break (week 17+) After 12-16 weeks of AOD 9604, discontinue it for a 4-week break while continuing tirzepatide

doi:10.1076/opep.10.4.215.15906

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