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ENS-CNS transmission occurs through a sequence of events: [1] local -synuclein seeds form in enteric neurons or associated mucosal cells under conditions of inflammation, oxidative stress, or exposure to microbial/toxic triggers

By simultaneously targeting multiple pathways, impairing mitochondrial function, and engaging immune mechanisms, this strategy is defining the core framework of next-generation precision therapies for CRC

MK-677 is an orally active, non-peptide growth hormone secretagogue that mimics ghrelin signaling

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CD14 + monocytes were isolated through positive selection