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Some protocols split the daily dose into two administrations (morning and evening) to maintain more consistent plasma levels, though definitive human PK data remain sparse as of 2026
However, in a subanalysis of participants with low vitamin B 12 status at baseline (n= 101), the B-vitamin supplementation slowed the decline in bone mineral density (total hip and femoral neck but not lumbar spine) (116)
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2.4 mcg in adults 6 Total body storage of vitamin B 12 ranges from 2 to 5 mg, and approximately half of it is stored in the liver
[11] In a study on segmented bone defects of rabbits, BPC-157 was shown to regenerate marrow, and thus induce greater bone healing
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