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Description

However, definitive NASH reversal requires liver biopsy showing resolution of inflammation and hepatocyte ballooningwhich wasn't performed in Phase 2a

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In 1982, the basic defect in cystinosis was elucidated as deficient or absent transport of cystine out of lysosomes [4]

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If "stronger" means more familiar biology, a clearer bridge from an already-approved GLP-1 backbone, and a less radical product concept, CagriSema looks stronger

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