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J., Gomes Dos Santos, A

nevertheless, a recent study has reported that this enzyme could be considered as an independent prognostic factor in colorectal cancer patients 52

Further, 12 of them have been recognized as putative drug transporters, including well-known P-gp encoded by the ABCB1 gene, MDR-associated protein 1 (MRP1, encoded by the ABCC1 gene), and ABC subfamily G member2, also known as breast cancer resistance protein, which is encoded by the ABCG2 gene [78, 79]

third, combination therapy may work differently in different phenotypes of type 2 diabetes[17]

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