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Preliminary data presented at the recent 85th Scientific Sessions of the American Diabetes Association showed that semaglutide 7.2 mg achieved a mean weight loss of 21%, outperforming the 2.4 mg dose
There is more direct animal experimental evidence on the effect of GLP-1RAs on HCC than on fibrosis
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Clinical experience suggests these patients should start preventive acid-suppressing medication (usually a PPI) at the same time they begin semaglutide, rather than waiting for symptoms to develop
Appetite suppression is observable within the first couple of months
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