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Use of fast-acting insulin within the preceding 12 months was an exclusion criterion because we wished to compare two different strategies of injectable therapy without other concomitant injectable glucose lowering medication

Hormone therapy in postmenopausal women and risk of endometrial hyperplasia

Prescribing authority remains independent of the platform and is exercised after enrollment rather than during sign-up

Twice-daily formulations like exenatide (Byetta) must be taken before meals

Liraglutide and exenatide are already off-patent and semaglutide will begin losing exclusivity in several large countries from 2026 (read more in our blog Off-patent semaglutide in 2026)