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Animal studies have also found that intermittent fasting lowers IGF-1 more effectively than long-term calorie restriction, but other studies have found no difference between the two (32, 33)

Additionally, the FDA recommends that these medications not be taken during pregnancy and be discontinued at least two months prior to pregnancy, because studies in rats, rabbits, and monkeys demonstrated that animals treated with these medications had higher rates of miscarriage, were born smaller, and were more likely to have birth defects

Available online at: (Accessed September 12, 2017)

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