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In 2023, GHK-Cu was placed on the FDA 503A list for compounded pharmaceutical substances under Category II restrictions

The mechanism centers on hepatocyte growth factor (HGF) and its receptor c-Met

One such specialized group of enzymes called Glutathione-S-Transferase (GST) attach glutathione to the byproducts of Phase 1 detoxification and neutralizes their toxic potential while simultaneously making these toxic substances more water-soluble and ready to be eliminated

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Argireline targets the same mechanism as Botox (neuromuscular signaling) but works on the surface level