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Doctors consider a patients comorbidities (coexisting, often chronic health conditions), as well as their goals, lifestyle habits and risk factors when deciding which option to choose

Whether synergistic, additive, or independent effects are produced in vivo depends on the specific research model, tissue type, and application method questions that remain open in the published literature for this specific blend ratio

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Even diet sodas, while calorie-free, may present tolerability issues due to carbonation and artificial sweeteners