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Figure 1 4 Discussion In HGSOC, the most common and deadliest subtype of epithelial ovarian carcinoma, preoperative prediction of resection status before neoadjuvant chemotherapy (NACT) and optimization of early diagnosis/treatment strategies have multifaceted importance in the clinical management of the disease

*Daily value not established

The GSH-to-GSSG ratio reflects cellular redox status

We therefore postulated that IGF-1R mAbs could represent a viable therapeutic tool to target IGF-1 action, and potentially mimic the beneficial effects associated with diminished IGF-1 signaling observed in animal models