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Remarkably, one study found that supplementing mice with GlyNAC, a compound that significantly increases GSH levels, prolongs rodent lifespan by 24%

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Therefore, by targeting cyclin-dependent kinases, miR-34a causes cell cycle arrest and promotes the senescence-associated secretory phenotype (SASP), which includes the release of growth factors, chemokines, and pro-inflammatory cytokines (Okada et al