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Higgins JPT, J Thomas, Chandler J, et al

Microchem J 184:108191 Hossain MS, Jahan S, Rahman SA, Rahman M, Kumar D, Paul S, Rajbangshi JC (2023) Design expert software assisted development and evaluation of empagliflozin and sitagliptin combination tablet with improved in-vivo anti-diabetic activities

Elegant animal models showed that intermittent access to sugar could produce behaviors resembling addiction

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At the moment, based on the dosing rationale that we presented today, we wouldn't anchor any expectations on efficacy signal from the 300 mg dose