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It is a potent antioxidant that plays a crucial role in detoxification, immune function, and combating oxidative stress

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Deficiency of Trem2 in macrophages worsens lipid accumulation and ferroptosis in TECs via IL-1-dependent CD36 upregulation, thus promoting DKD progression (201)

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Our cells have adapted to this potential toxicity by storing cysteine in the form of glutathione (GSH) [8] , which is far more stable to oxidation