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GLP-1, oxyntomodulin and exendin-4, whose affinities are influenced by the presence of G s , promote a more closed bundle relative to exendin-P5, whose affinity is less sensitive to the presence of G s

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Discussion Our analysis of Truveta Data reveals notable trends in the prescribing patterns of AOM semaglutide compared to AOM liraglutide, among adolescents aged 12 to 17 years between January 2021 and March 2025