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Li M, Zhao L, Liu J, Liu A, Jia C, Ma D, et al
These show that taking a 300-3,000mg berberine a day orally is associated with modest reductions in body mass index (BMI), waist circumference and body weight (around 3kg)
10.1016/j.jpsychires.2006.07.013 J Psychiatr Res
FIGURE 5 3.6 FOXO4-DRI promotes apoptosis in senescent cells As established in prior research, FOXO4-DRI competitively binds to p53 with high affinity, thereby disrupting its nuclear interaction with FOXO4
A final limitation is the use of sitagliptin as a comparator
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