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The evolutionary distances were computed using the Poisson correction method and are in the units of the number of amino acid substitutions per site 43
Many patients see changes within the first month
IL-17A is increased in the serum and in spinal cord CD8 and mast cells of ALS patients
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The inability to maintain reduced glutathione in RBCs leads to increased accumulation of peroxides, predominantly H 2 O 2 , that in turn results in a weakening of the cell wall as a result of membrane lipid peroxidation resulting in concomitant hemolysis
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