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Hormonal changes are among the most significant factors
Reference: Once-weekly semaglutide 72 mg in adults with obesity (STEP UP): a randomised, controlled, phase 3b trial by Sean Wharton, Paula Freitas, Jran Hjelmesth, Maria Kabisch, Kristian Kandler, Ildiko Lingvay, Maria Quiroga, Julio Rosenstock and W Timothy Garvey, 14 September 2025, The Lancet Diabetes & Endocrinology
When eating less, its important to pay attention to what youre eating to ensure youre getting enough essential nutrients
What protein and calorie range fits my medication, weight-loss pace, kidney function, labs, and activity
Continuing mindful eating, portion control, regular exercise, and possibly transitioning to another tool (like a different medication or increased lifestyle intervention) can help maintain weight [intermountainhealthcare.org]
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