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Similar to the findings of other studies in the STEP trial program 7,27 , exploratory outcomes showed that in the semaglutide group 80% of participants with prediabetes at baseline reverted to normoglycemia by the end of the trial (compared with 37% of those receiving placebo), while 99% of participants with normoglycemia at baseline maintained normoglycemia at the end of the trial (compared with 86% with placebo)

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To maintain adequate B12 levels, oral supplements may require more constant daily ingestion

Pregnancy and breastfeeding require individualized risk-benefit assessment

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