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In clinical trials, GLP-1 RAs were shown to significantly lower blood pressure (BP) in addition to HbA1c and body weight (BW), indicating the possibility as anti-hypertensive medication of type 2 DM individuals

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Beyond weight management, retatrutide exhibits profound metabolic benefits that extend to cardiovascular health and glycemic control

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Fatty acid side chain: A C-18 diacid chain is attached to the C-terminus, extending the half-life to approximately 7 days and enabling once-weekly dosing