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Some are also approved to reduce the risk of major adverse cardiovascular events (MACE) like heart attack and stroke, support kidney protection, treat obstructive sleep apnea (OSA) via significant weight loss, and help with metabolic dysfunctionassociated steatohepatitis (MASH) in certain patients

Its estimated that medication is only responsible for 1.4 to 2 percent of cases

This is achieved through increased pancreatic and plasma levels of glucagon-like peptide-1, a precursor for SCFAs, which exert cardioprotective effects ( Bifidobacterium bifidum , Butyrivibrio , and Megasphera

Diabetologia 45 , 11111119 (2002)

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