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The short half-life of native GLP- 1-based therapy in the circulation (approximately two minutes after intravenous administration and one to five hours after subcutaneous administration) posed a problem during its early development [9]

Understanding where and how changes occur helps set realistic expectations and explains why two people who lose the same amount of weight can look very different in their before and after photos

A., Nilsen, K

This prevents repeated puncturing of a single vial and reduces the risk of contamination