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That said, the clinical message remains unchanged: they are contraindicated in pregnancy and require an appropriate wash-out before planned conception

If reactions persist despite rotation, split the 100mg dose into 50mg twice daily (morning and evening) or switch to oral administration at 150mg to bypass subcutaneous absorption entirely

Samples were exposed to H 2 O 2 or buffer (blank control), and absorbance was recorded immediately at 240 nm in eight intervals ranging from 1 to 40 s