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The medication restores appetite regulation that estrogen previously helped maintain, explaining why many menopausal women experience particularly dramatic improvements in hunger control
The effect accumulates over time, allowing sustained weight loss without the constant hunger that typically accompanies traditional dieting
It was found that R6/2 mice exhibited increased intestinal permeability and reduced colon length at 16 weeks of age (early-mid disease stage), as compared to age-matched WT mice
Some protocols run 50100 mcg but the risk/benefit ratio shifts considerably above 50 mcg without meaningful additional evidence of proportional benefit
Those taking more of the drug did show more improvement, though
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