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The present review provided an overview of studies with SGLT2 inhibitors, and discussed the synergistic mechanisms of SGLT2 inhibitors combined with ACEI/ARBs, dipeptidyl peptidase-4 (DPP-4) inhibitors, glucagon-like peptide-1 receptor agonists (GLP1-RAs) and mineralocorticoid receptor antagonists (MRAs) in the treatment for DKD
Strips were washed in SDSPAGE buffer and resolved by SDSPAGE before immunoblotting
Key pathways such as nitric oxide and the VEGFR2 receptor seem to be involved in this process