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Furthermore, NHEJ-mediated knock-in, including HITI, supports the insertion of large DNA fragments (up to ~50 kb), making it an exceptionally powerful tool for in vivo genome editing therapies 12
These results suggest that GLP-1R agonists are able to improve cognitive function by attenuating the oxidative stress and mitochondria dysfunction in CNS
These findings, taken together with the neuroprotective actions of IGF-I[55, 56], suggest that astrocytes are relevant in ameliorating brain injury
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