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ZepBound, launched for obesity in late 2023, quickly added hundreds of millions in sales by mid-2025, its global sales were already in the hundreds of millions as clinics rolled out the new weight-loss injection
Eric Burnett , an internal medicine doctor at an academic medical center in New York and a health communicator on social media "To frame this class of drugs as 'fat shots' is not only fatphobic, but also flattens all of the benefits and uses of these medications." "GLP-1s have a ton of different applications
As of April 2026, Wegovy appears on approximately 78% of Express Scripts-managed commercial formularies according to analysis of formulary files submitted to CMS (Conklin et al., Health Affairs 2025)
Studies show it supports cardiovascular health by improving flow-mediated dilation in subjects with risk factors, enhances immune function through elevated natural killer cell activity, and contributes to skin health by protecting against oxidative damage while supporting collagen production
In addition, some people naturally have a higher or lower production of glutathione due to genetic variations
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