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Future trials should also measure important outcomes such as the clinical signs and symptoms of vitamin B 12 deficiency, health related-quality of life, socioeconomic effects, and report adverse events adequately, preferably in a primary care setting. Clinical practice guidelines British Columbia Medical Services Commission (MSC)
10.2903/j.efsa.2015.4150 20 EggerM.Davey SmithG.SchneiderM.MinderC
The absence of adequate B12 in your system can manifest in various, often debilitating waysfrom stomach and chest discomfort to severe fatigue, headaches, and even neurological symptoms
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