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In contrast, BRP appears to act specifically in the hypothalamus, which controls appetite and metabolism. Svensson has co-founded a company to launch clinical trials of the molecule in humans in the near future
The standard injection schedule reaches a target maintenance dose of 2.4 mg after approximately 16 weeks
Acta 1833 , 34483459 (2013)
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While Zepbound can be used in patients with renal impairment without dose adjustment, the FDA recommends monitoring renal function in patients with renal impairment who report severe gastrointestinal adverse reactions
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