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Maximum Dose Reached Over 1 year of follow-up, most patients in the semaglutide 2.4 mg cohort (83.5%) reached the maximum dose of 2.4 mg, with an additional 11.2% of patients reaching a dose of 1.7 mg (Table 4)

References Markle HV, Greenway DC

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Water retention or mild bloating: Small amounts of fluid retention can occur when starting peptide analogues of growth hormone because growth hormone causes sodium and water retention in the tissues, resulting in slight puffiness or bloating