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The digested samples were lyophilized with a speedvac and resuspended in 0.1% trifluoroacetic acid (TFA) and 5% acetonitrile
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This hepatic enzyme converts UA to allantoin, and its absence results in serum UA concentrations relatively elevated by, typically, an order of magnitude
Table 1 Summary of metabolic approaches in ALS and their effects in models of ALS and patients with ALS
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