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298 Consequently, the primary goal of second-generation mTOR inhibitors is to simultaneously target both the mTORC1 and mTORC2 signaling pathways, as well as their feedback loops, which were not addressed by first-generation inhibitors
doi: 10.1007/s00240-011-0448-9 70 PizzinoGIrreraNCucinottaMPallioGManninoFArcoraciVet al
Rosenbloom AL (2009) Mecasermin (recombinant human insulin-like growth factor I)
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