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10.1016/s1499-3872(11)60085-4 106 WangW.GuanC.SunX.ZhaoZ.LiJ.FuX.et al (2016)
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GLP-1R agonists may exert antidepressant effects by modulating inflammatory processes in the brain Chronic inflammatory processes in the brain associated with excessive activation of microglia and increased production of pro-inflammatory cytokines are one of the key factors leading to the development of depressive symptoms, as patients suffering from this mental illness are very often characterized by elevated levels of tumor necrosis factor-alpha (TNF-), interleukin-6 (IL-6), interleukin-1 beta (IL-1), C-reactive protein (CRP), and interferon-gamma (IFN-) in the cerebrospinal fluid and the blood [59,60,61]
Vision changes GLP-1s can affect the vision in several ways, including worsening vision in some cases due to rapid blood sugar correction or insufficient blood flow to the optic nerve