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These modifications significantly reduce binding affinity for IGF binding proteins (IGFBPs 1 through 6), extending functional availability in in vitro assay systems
Methods Plasmid construction Amino acid mutations to switch Rex-domain specificity from NAD to NADP were selected based on a previous screen 15
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The results showed that 10 peptides (LLLPH, KDFPPR, DDFFL, ADFYNPK, IIGGI, DTPMIG, SVVDM, LVSPP, C(+57.02)ADLF, and VIVEL) which are rich in hydrophobic amino acids were identified in the fraction F3 by LC-MS/MS
What Research Shows about IGF-1 LR3
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