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Younger patients who achieve substantial weight loss and demonstrate capacity for sustained dietary and exercise changes may be candidates for medication discontinuation with close monitoring

Clinical trials demonstrate improvements in several metabolic parameters, including reduced hemoglobin A1c levels (typically 1.0-1.6% depending on baseline levels and dosage), decreased fasting plasma glucose, and modest improvements in lipid profiles

ISPAD clinical practice consensus guidelines 2018: diabetes technologies

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Changes in serum calcitonin concentrations, incidence of medullary thyroid carcinoma, and impact of routine calcitonin concentration monitoring in the exenatide study of cardiovascular event lowering (EXSCEL)