It did not affect T cell uptake due to compensatory upregulation of the glutamine transporter SLC6A14 in CD8 + T cells, which increased CD8 + T cell activation and glutathione synthesis (Jin et al., 2020)
Ayton S, Lei P, Duce JA, Wong BXW, Sedjahtera A, Adlard PA et al
Required evidence may include clinical studies, extensive post-marketing use data, expert advice, and the views of relevant health professionals and public associations
Vitamin C - In 48 individuals with ascorbate deficiency taking 500 or 1000 mg per day of vitamin C for 13 weeks led to an 18% increase in lymphocyte Glutathione levels
Nausea, stomach cramping, and diarrhea occur, especially when starting at high doses or taking more than 500mg in a single sitting