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Preclinical research indicates that intra-articular (IA) liraglutide attenuates synovial inflammation, decreases catabolic markers such as ADAMTS-5, and limits cartilage and bone damage across three experimental OA models, including MIA (mono-iodo-acetate), DMM (destabilization of the medial meniscus), and collagenase II-induced OA

Zhou X, Liao J, Lei Z, et al

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10.1016/S0008-6363(96)00245-3 48

Therefore, its always advisable to consult with healthcare professionals or dietitians who can provide tailor-made advice, considering both your health goals and the effects of semaglutide