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Generally safe to combine, but monitor skin closely for any unexpected changes

Transplantation of UC-MSCs on collagen scaffold activates follicles in dormant ovaries of POF patients with long history of infertility

This may be due to the fact that bile acids entering the intestine stimulate intestinal secretion and expression of the gut-derived hormone FGF19 via bile acid-FXR signaling (Mulla et al., 2019), which stimulates hepatic glycogen synthesis in an insulin non-dependent manner, restrains hepatic gluconeogenesis, and exerts hypoglycemic effects

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Physicians who performed baseline and outcome assessments were also blinded to the randomization status