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Clinical Trials Identifier: NCT06075667 Trial Name: A Study of Tirzepatide (LY3298176) Once Weekly in Adolescent Participants Who Have Obesity or Overweight With Weight-Related Comorbidities (SURMOUNT-ADOLESCENTS) Trial Sponsor: Eli Lilly and Company What is the aim of the study

Studies in the model organism Caenorhabditis elegans have demonstrated that different FOXO isoformsparticularly DAF-16Aexert a significant influence on lifespan extension by activating or repressing specific genes such as gst-20 and srr-4, which either promote or inhibit longevity-associated mechanisms

Moving Forward Together The Foundation for Prader-Willi Research is supporting the PWS Clinical Investigation Collaborative (PWS-CLIC) to develop a dedicated GLP-1 data module within the PWS-CLIC database to meet this need

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