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P., Komninou, D., Leutzinger, Y., Kleinman, W., Orentreich, N., & Frei, B

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Quick Facts: Melanoma Causes and Risk Factors The Biological Mechanism: Melanoma forms when cellular DNA sustaining severe damage prompts melanocytes to mutate and multiply uncontrollably, forming localized skin tumors that can eventually infiltrate the lymphatic system or bloodstream Common Appearance: Characterized by the sudden appearance of a new skin growth or noticeable changes to an existing mole's size, shape, color, or texture Frequent Locations: Occurs most commonly on the back in men and on the lower legs in women Controllable Risk Factors & Environmental Triggers Ultraviolet (UV) Exposure: Frequent, intense exposure to UV radiation via natural sunlight remains the leading cause of preventable DNA damage, particularly during peak hours from 10 a.m

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Insulin is released in response to increased blood sugar, such as when food is ingested