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Te dose of 2g iss approved by the French Food Safety Agency (AFFSA) and Environmental and Occupational Health and Safety (ANSES) It is suggested that the supplementation of creatine should be selected very carefully, under the consultation of a professional nutritional coach, because many of the creatine products out on the market contain impurities, absorb poorly, and lead to excessive water retention

Research is ongoing, but more evidence is needed before regulators consider approval

The most crucial lesson is to prioritize approved treatments, and exercise caution

Inhibition of the mitochondrial permeability transition by cyclosporin A during long time frame experiments: Relationship between pore opening and the activity of mitochondrial phospholipases

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