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A standard refrigerator (not the freezer) is ideal for long-term storage, but it will be fine at room temperature for several weeks without any significant degradation

In the pathological environment of RA, due to synovial inflammation, the osteoclast-osteoblast axis is severely disrupted, leading to enhanced osteoclast function and RA-related bone destruction 10

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This is particularly relevant during dose escalation periods when gastrointestinal symptoms tend to be most pronounced