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Patients should initially consult their GP, who can refer to local NHS eating disorder services, community mental health teams, or specialist weight management services as appropriate

Importantly, the effect is most pronounced in proximal colon cancers, a region historically less protected by screening alone

Practical timeline expectations For researchers who decide to proceed with a combined protocol despite the unknown risks, realistic timeline expectations help set appropriate milestones for evaluation

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Start Small: Observe tolerance as well as response with a 0.25mg0.5mg dose