As neuroinflammation progresses, glial cells release cytotoxic factors, disrupt the extracellular matrix, and contribute to glutamate receptor-mediated excitotoxicity, all of which accelerate RGC loss (123)
Similar findings were suggested by Akbari et al
For example, topical minoxidil is FDA-approved for androgenetic alopecia in men and women and helps extend the growth (anagen) phase of the hair cycle
Acknowledgements The present study was funded by the National Research Foundation of Korea through the Basic Science Research Program (NRF-2017M3A9B4061890, NRF-2017R1D1A1B03035059, NRF-2017M3A9D8062960, and NRF-2018R1A2B3008541)
Patients, Material, and Methods Between 2015 and 2016, 66 patients with ME/CFS were studied ( The usual care of the study participants included a detailed clinical history, physical examination, vitamin B12 serum levels (pmol/l), and ECG and echocardiography