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The findings are compatible with the clinical data showing that fibroblasts derived from a patient with homozygous A71P mutant in CHCHD2 show reduced cIV activity in addition to cI deficiency (Lee et al., 2018)
Regarding safety, the majority of reported adverse events were mild to moderate, ranging from 88% to 96%, depending on the specific study group
Thus, eryptosis promotes the formation of EVs
The production of melanin is triggered by an enzyme called tyrosinase
Afshin-Majd S, Bashiri K, Kiasalari Z, Baluchnejadmojarad T, Sedaghat R, et al
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