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The mechanism of action involves dual agonism at both glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptors
The right treatment depends on the individual patient
Ongoing studies continue to monitor for potential rare side effects, including effects on the pancreas, thyroid, and cardiovascular system
The effect of metformin in overweight patients with type 1 diabetes and poor metabolic control
In Phase 3 trials (n=412), it produced a 15.2% reduction in visceral fat and a significant increase in IGF-1 (Falutz et al., JAMA 2007At French Peptides, it is available exclusively for research
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