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Depending on the patient, monitoring may include: Weight trends Waist circumference Blood pressure Glucose and A1C Lipids Liver markers Kidney markers Thyroid markers when appropriate Nutrient markers when indicated Hormone considerations when relevant Adjust the Plan as the Body Changes A patients needs at the start of treatment may not be the same after losing 20, 40, or 60 pounds

Christopher Hanley is an associate professor and chair of clinical pharmacology at Manhattanville Universitys School of Nursing and Health Sciences in Harrison, New York

Did the authors limit the types of persons with Parkinsons disease who were allowed to enroll in the trial

If you must dose early, the protocol is: Limit early dosing to 24 hours or less whenever possible If dosing 24 to 48 hours early is unavoidable, eat smaller meals for the next 3 days and avoid high-fat foods Have an antiemetic available (ondansetron 4 mg as needed, if prescribed by your provider) Return to your regular schedule the following week (do not shift your permanent schedule forward) If you experience severe nausea or vomiting, contact your provider before the next dose What most articles get wrong about "missed dose" guidance Most patient-facing articles on Zepbound dosing cite the package insert guidance for missed doses, which states: "If a dose is missed, administer as soon as possible within 4 days (96 hours) after the missed dose